Sudarshan A. Shetty
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Sudarshan A. Shetty

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I’m a microbiome scientist interested in exploring the potential of microbiome in improving health and well-being. I have >9 years of experience in human microbiome research. In these years, I have acquired skills in experimental design, anaerobic microbiology, multi-omics data analytics, tool development and led collaborative projects.

I received my PhD in Human gut microbiology at the Laboratory of Microbiology, Wageningen University and Research, with Prof. dr. Willem M De Vos, Prof. dr. Hauke Smidt and Prof. dr. Leo Lahti. I studied the human gut microbiome at multiple levels from single bacterium, synthetic microbiomes to ecosystem level. Together with Leo Lahti, I have co-developed R packages that are widely used in microbiome research.

Apart from research, I enjoy creating acrylic paintings and consider my self an amateur chef.

Experience

  • February 2021 - February 2023
    Post Doctoral Researcher at Medische microbiologie en infectiepreventie, Groningen and The Netherlands National Institute for Public Health and the Environment (Rijksinstituut voor Volksgezondheid en Milieu).

  • February 2020 - Jan 2021
    Post Doctoral Researcher at University Medical Center, Utrecht and Netherlands National Institute for Public Health and the Environment (Rijksinstituut voor Volksgezondheid en Milieu).
    • Immune response in elderly subjects receiving vaccine(s). Investigation of various immune parameters and microbiota.

  • March 2019 - Jan 2020
    Post Doctoral Researcher at Laboratory of Microbiology, Wageningen University and Research.
    • Design and development of synthetic human gut microbiomes.
    • Developing multi-omics integrative biodiscovery pipelines for efficient utilization of synthetic microbiomes in a variety of biotech applications.

  • August 2014 - March 2019
    PhD, Laboratory of Microbiology, Wageningen University and Research.
    • Used a combination of genomics, proteomics and anaerobic culturing to elucidate the physiology of core human intestinal bacteria.
    • Used a combination of in-silico and in-vitro approach to develop a defined consortium of human intestinal microbiome.
    • Developed analytical pipelines in R for high-throughput sequencing data (primarily 16S rRNA gene amplicon).

  • June 2012 - June 2014
    Junior Research Fellow, National Centre for Cell Science.
    • Developed 48-well plate screening method for bio-molecules from bacteria isolated from various ecological niches of Western Ghats.
    • Genome sequencing and analysis of potential novel anaerobic bacteria isolated from feces of healthy human subjects.
    • High-throughput sequencing and data analysis of microbial community in human subjects with different dietary habits (The Pune Microbiome Study).